Mithra Announces Valorization of French Subsidiary


Mithra (Euronext Brussels: MITRA), a company specialized in Women’s Health, today announces that it successfully divested its French affiliate, Mithra France.

The sale consists of two agreements. A first contract is closed with Laboratoire CCD, a French-based Women’s Health player, and concerns the transfer of marketing authorizations (MAs) for 4 products, including Tibelia®, Mithra’s tibolone-based product for the relief of postmenopausal symptoms and prevention of osteoporosis in post-menopausal women. Moreover, the contract with CCD also contains a 10-year exclusive License & Supply Agreement for Tibelia® in France. Mithra is eligible for an upfront payment as well as future royalties for the 4 products over a period of 5 years, next to annual revenues following the commercial launch of Tibelia® in France, which is expected in H2 2018. The French market for Livial®, Tibelia®’s originator product, currently represents approximately EUR 2.5 million in annual sales.


Secondly, Mithra concluded a share purchase agreement for Mithra France with Theramex, whereby Theramex will take over the subsidiary, including its pharmaceutical license. As announced earlier this year, Theramex consolidates the non-US Women’s Health assets acquired from Teva by CVC Capital Partners.


Financial details of the agreements were not disclosed. The sale of the French subsidiary fits into Mithra’s strategy to maximize the value of its non-core assets, and to fully focus on the development and partnering for its key E4-based programs, viz. Estelle® for contraception and Donesta® for menopause.


François Fornieri, CEO of Mithra, commented:

“The sale of the French subsidiary and the attractive financial deal terms reflect our ability to create value even from our non-core assets. Importantly, this divestment enables us to further pursue our strategic focus and dedicate a maximum amount of time and resources to our pivotal E4 studies.”


Mithra (Euronext: MITRA) is dedicated to providing innovation and choice in Women’s Health, with a particular focus on fertility, contraception and menopause. Mithra’s goal is to develop new and improved products that meet women’s needs for better safety and convenience. Its two lead development candidates – a fifth generation oral contraceptive Estelle® and next-generation hormone therapy Donesta® - are built on Mithra’s unique natural estrogen platform, E4 (Estetrol). Mithra also
develops, manufactures and markets complex therapeutics and offers partners a complete spectrum of research, development and specialist manufacturing at its CDMO.

Mithra was founded in 1999 as a spin-off from the University of Liège by Mr. François Fornieri and Prof. Dr. Jean-Michel Foidart. Mithra is headquartered in Liège, Belgium. Further information can be found at:



Interested in a regular update of the Life Sciences and biotech sector in Flanders?